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Developing New Theoretical Folding Models of DNA and RNA with Mathematica

Guillame Santini, Université Paris 13
Jean Cognet, Sorbonne Université

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"Mathematica is very important to the work of a researcher. We can quickly build a small interface to test, view and manipulate ideas in real time, and no other software offers this."
The Mathematica Edge
  • Rapidly search the human genome
  • Instantly visualize protein sequence alignments
  • Improve productivity, debug and write documentation with advanced tools available in Wolfram Workbench


As researchers studying theoretical folding models of DNA and RNA, Guillame Santini and Jean Cognet require easy access to predefined mathematics and visualization functions. They also need a flexible platform that makes it possible for them to work with multiple programming approaches without impeding workflow.


Mathematica provides a complete work environment for Santini and Cognet, making it ideal for research-related queries. In fact, Cognet adds, "For me, Mathematica is the best system out there." It enables them to write complex modeling programs that compute quickly and produce detailed graphic visualizations of their theories.


Santini and Cognet note that Mathematica is a very important part of their work. It gives them flexibility and the ability to devote more time to research rather than wasting time on computation. In addition, when combined with Workbench—Wolfram's integrated development environment for creating applications—they are able to integrate all of their documentation and easily share their findings with others.

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