The use of liver-specific contrast agents in combination with magnetic resonance imaging (MRI) has recently emerged as a non-invasive approach to assess liver function. Here, we create a pharmacokinetic model to describe the distribution and transfer rates of contrast agent between different parts of the body. Using MRI data, the model is then calibrated to investigate the quantitative difference between a non-diseased population and diseased patients suffering from liver fibrosis stage 4.
Create Compartmental Biological Models
Perform Monte Carlo simulations
Dynamically visualize contrast agent fluxes
Programmatically control simulations
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